Ikebukuro to Universal Studio

What is the best way to get to Universal Studios from Ikebukuro? I'm based in Ikebukuro for all of my stay other than Universal studios

Shinkansen to Osaka:

http://www.japan-guide.com/e/e4006.html

And then local trains to USJ:

http://www.japan-guide.com/e/e4021.html

Alternatively you could fly and bus.

By the way, you are aware that USJ is in Osaka and not at all close to Ikebukuro, which is in Tokyo? It would be about 7 total hours of travel time to do as a daytrip.

Yes..I know it is away from Tokyo..but it is the only place outside Tokyo I want to visit

Would be better to stay one night in Osaka or make it a day trip?

You would be better off spending the night. You might want to consider one of these packages:

http://www.japanican.com/tours/list.aspx?kw=shinktusj